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A Non-Invasive Alternative

The Leksell Gamma Knife® Perfexion™  is an effective, non-invasive alternative or supplemental treatment to traditional brain surgery. This highly sophisticated technology precisely directs focused radiation to specific targets in the brain. Typically performed in a single outpatient treatment session without general anesthesia, this proven stereotactic radiosurgical procedure helps patients avoid incisions, blood loss, scarring, and long hospital stays while minimizing surgical complications. For many conditions, Gamma Knife treatment is the most accurate form of stereotactic radiosurgery available. See the FAQs for more detailed information about the Gamma Knife.

Conditions treated with the Gamma Knife Perfexion include:

Candidates for Gamma Knife Treatment

Brain tumors and vascular disorders account for the majority of radiosurgical procedures performed today.  Radiosurgical treatment provided by the Gamma Knife Perfexion is effective at controlling tumor growth, and hemorrhaging from vascular malformations. This treatment procedure targets lesions in the brain so exactly that the risk of harming healthy tissue is minimized. In certain cases, Gamma Knife treatment may serve as an adjunct to standard neurosurgical therapy or as the preferred course of treatment when further traditional therapy is not recommended.

Treatment with the Gamma Knife Perfexion is often the preferred alternative for patients who are not candidates for conventional neurosurgery or radiation therapy. It also may be recommended as an additional therapy for individuals who have already undergone surgery, chemotherapy or radiation and require further treatment.

The Gamma Knife may also be recommended for patients with the following conditions:

  • Tumors or vascular malformations that are surgically inaccessible
  • Risk factors that make surgery inadvisable
  • Need for an additional dose of radiation following conventional radiation therapy
  • Recurrent tumors
  • Facial pain

Our multidisciplinary team (including neurosurgeons, radiation oncologists, a physicist and nurses) evaluates each patient to determine whether Gamma Knife treatment is the best option. The patient's medical history is reviewed, along with imaging studies and information provided by the patient's physician. If Gamma Knife treatment is not considered appropriate, the team will suggest an alternate treatment option.

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Conditions Treated


World wide statistics.
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Malignant tumors 42%
Achieves control rates of 80-85 percent for metastatic tumors, essentially comparable to open surgery – with fewer risks and shorter hospital stays.
Benign tumors 35%
Has a 90 percent control rate at ten-year follow-up.
Vascular abnormalities 14%
Results in complete obliteration of arteriovenous malformations in 60-70 percent of patients within two to three years.
Functional Disorders 8%
For trigeminal neuralgia, most patients have initial pain relief in over 80 percent of patients; long-term pain relief without medications occurs in 63 percent of patients at four-year follow-up.
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